Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 100 |
Cambridge, Massachusetts
Overview: The Quality Control Operations (QCO) Analyst II plays a crucial role in supporting the department's efforts to maintain the highest standards of quality and compliance from development through to commercialization. In addition to ...
4h
| Job Type | Full Time |
Cambridge, Massachusetts
The Sr. Manager, Clinical Operations is responsible for leading the operational planning and execution of global clinical trials from study start-up through closeout. This role provides leadership to cross-functional trial teams, ensuring t...
13h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview The Process Equipment Technician will support lab and facilities operations at the Alnylam Kendall Campus on the weekend shift. This encompasses a wide range of facilities and engineering maintenance lab equipment, & utilities. Res...
13h
| Job Type | Full Time |
Field Reimbursement Manager - Northwest
Cambridge, Massachusetts
Overview: The Field Reimbursement Manager (FRM) serves as the access and coverage subject matter expert for Alnylam products. The FRM educates healthcare providers (HCPs) and office staff on reimbursement processes, payer requirements, cove...
1d
| Job Type | Full Time |
Associate Director, Clinical Science
Cambridge, Massachusetts
Overview: The Associate Director (AD), Clinical Science will be a member of the global clinical development team, working closely with other members of the clinical research group within clinical development (medical lead, medical monitor, ...
1d
| Job Type | Full Time |
Director, Platform Infrastructure
Cambridge, Massachusetts
Overview The Director, Platform Infrastructure will lead Alnylam's enterprise infrastructure platform strategy, building the secure, resilient, and scalable technology foundation that supports enterprise applications, data and AI, Science, ...
2d
| Job Type | Full Time |
Associate Director, Cyber Defense - Staff Incident Responder
Cambridge, Massachusetts
Overview Alnylam is pioneering RNAi therapeutics and scaling rapidly across research, development, manufacturing, and global commercialization. The Associate Director, Cyber Defense - Staff Incident Responder will play a critical role in pr...
2d
| Job Type | Full Time |
Director, AI & Technology Governance, Ethics and Compliance
Cambridge, Massachusetts
Overview Alnylam is seeking an experienced Artificial Intelligence (AI) and emerging technology governance leader to establish and mature the Company's enterprise AI governance. Reporting to the Head of Privacy, AI and Data Governance, Trai...
5d
| Job Type | Full Time |
Senior Associate Scientist, Biology
Cambridge, Massachusetts
Overview The Research Department at Alnylam is seeking a highly motivated Senior Associate Scientist to join our innovative Next Wave, Target Discovery and Validation team. Our mission is to discover novel genetically informed targets and e...
6d
| Job Type | Full Time |
Associate Scientist II, Biology
Cambridge, Massachusetts
Overview The Research Department at Alnylam is seeking a highly motivated Associate Scientist II to join our innovative Next Wave, Target Discovery and Validation team. Our mission is to discover novel genetically informed targets and exper...
6d
| Job Type | Full Time |