New

Intern, Drug Innovation

Alnylam Pharmaceuticals
United States, Massachusetts, Cambridge
675 West Kendall Street (Show on map)
Mar 25, 2026
We are seeking an experienced oligonucleotide chemist or pharmaceutical chemist with expertise in design, synthesis, analysis of oligonucleotides. The candidate should have expertise in scientific literature, database and patent search; modern analytical and separation techniques and instrumentation. Successful candidate will work in a multidisciplinary environment involving discovery and development of RNAi chemical modifications, delivery agents and conjugates. Summary of Key Responsibilities: Synthesis of oligonucleotides and conjugates; knowledge in formulation, analysis of drug delivery systems and conjugates for nucleic acids. Purification of oligonucleotides using modern separation techniques Analysis and characterization using modern analytical techniques (NMR, MS, HPLC, IR, etc.). Multitasking and multidisciplinary expertise Expertise in scientific data base, literature survey and patent search Manuscript Writing skills Learning Outcomes siRNA synthesis siRNA analytical chemistry and characterization siRNA formulations Qualifications Advanced degree inoligonucleotide chemistry or pharmaceutical chemistry. Graduate or PhD candidates preferred. Hands-on experience on separation and analytical instrumentation and scientific database search Instrumentation skills, desire to learn bioassays, oligonucleotide synthesis Legal authorization to work in the U.S. At least 18 years of age prior to scheduled start date U.S. Pay Range $30-$35/hr >