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Bioinformatics Programmer

University of California - San Francisco
United States, California, San Francisco
Dec 21, 2024

Bioinformatics Programmer

CoLabs Admin

Full Time

82981BR

Job Summary

We are seeking a bioinformatics programmer with a B.S., M.S., or equivalent, in fields relating to molecular biology, bioinformatics or computer science. Working as part of a multidisciplinary group and independly, the bioinformatics programmer will perform statistical analyses of high throughput genomics data, especially bulk-cell and single-cell RNA-sequeing data, by developing novel, and using or adapting existing computational pipelines and algorithms. The job candidate will write code to process genomic data sets, generate reports, and present the results to collaborators. S/he will work from standard analysis pipelines and modify code to fit individual projects. S/he will interact closely with core lab members and collaborate with other bioinformaticians doing similar work at UCSF and elsewhere.

Primary job responsibilities:

  • Carrying out data analysis on bulk cell and single cell RNA-seq projects.
  • Carrying out analysis of ATAC-seq, ChIP-seq, Whole genome sequencing and other NGS approaches.
  • Developing novel workflows for NGS sequencing analysis.
  • Communicating and providing results to researchers using the core.
  • Provide bioinformatic support during sequencing QC.
  • Support research efforts of labs utilizing next generation sequencing technologies.

Job requirements:
  • Understanding of basic molecular genetics.
  • Experience working with next generation sequencing (NGS) methodologies and applications.
  • Proficient in Python and R.
  • Experience working in Linux/Unix systems, including using command line tools.
  • Excellent verbal and written communication skills.
  • Strong organizational and interpersonal skills for working in a multidiscipline and collaborative team.

The CoLabs
The CoLabs are a collection of integrated laboratories specializing in infrastructure or technologies. It seeks to revitalize the model for core resources by capitalizing on critical personnel and cutting-edge technologies and driving collaboration across disciplines. The model will house all CoLabs teams in a contiguous space and create a set of common pipelines and workflows in one centralized locale. It will recruit and retain world-class staff through project engagement, backstopped "tenure," and annual operational funds. It will develop and invest in transformative methods and technologies.

In its current form, the CoLabs consolidate three existing groups, Genomics, Flow Cytometry, and Biological Imaging Development (BIDC), and establish two new ones, Disease to Biology (D2B) and Data Science (DS), placing them all under one roof. The CoLabs will help organize and integrate the UCSF community through common pipelines and data curation around a set of collaborative "CoProjects" that will tackle fundamental questions in the field. While CoProjects are investigator-driven, the day-to-day operations must be managed and run through the cutting-edge CoLabs, which house world-class staff and technologies.

Genomics CoLab
The Genomics CoLab serves as an innovative hub of molecular biologists, genomicists and bioinformaticians engaging in collaborative research across UCSF campuses. At the Genomics CoLab, we emphasize in the development of novel genomic approaches and providing advanced genomic and bioinformatic resources for investigators who wish to integrate modern genomic approaches into biological research. These approaches include bulk- and single-cell RNA-seq, small RNA-Seq, ChIP-Seq, ATAC-seq and whole exome/genome sequencing. We are also actively working on integrating novel genomic methods such as combinatorial genomic methods, special transcriptomics, and new epigenomic approaches.
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Working as part of a multidisciplinary group, the bioinformatics programmer will perform statistical analyses of high throughput genomics data by developing novel or adapting and using existing computational algorithms. S/he will write code to process genomic data sets, generate reports, and present the results to collaborators. Working independently, s/he will work from standard analysis pipelines and modify code to fit individual projects. S/he will interact closely with core lab members and collaborate with other biostatisticians doing similar work at UCSF and elsewhere. The Bioinformatic Programmer will also maintain workflows in a version-controlled environment (GitHub or equivalent) and periodically update the core website to reflect changes in work flows and services.

The final salary and offer components are subject to additional approvals based on UC policy.

Your placement within the salary range is dependent on a number of factors including your work experience and internal equity within this position classification at UCSF. For positions that are represented by a labor union, placement within the salary range will be guided by the rules in the collective bargaining agreement.

The salary range for this position is $75,700 - $104,400 (Annual Rate).

To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html

Department Description

The Genomics CoLab serves as an innovative hub of molecular biologists, genomicists and bioinformaticians engaging in collaborative research across UCSF campuses. At the Genomics CoLab, we emphasize in the development of novel genomic approaches and providing advanced genomic and bioinformatic resources for investigators who wish to integrate modern genomic approaches into biological research. These approaches include bulk- and single-cell RNA-seq, small RNA-Seq, ChIP-Seq, ATAC-seq, whole exome/genome sequencing and spatial transcriptomics. We are also actively working on integrating novel genomic methods such as combinatorial genomic methods, special transcriptomics, and new epigenomic approaches such as CUT&TAG.

Required Qualifications


  • Bachelor's degree, or equivalent experience, in molecular biology, bioinformatics, computer science or related field
  • Minimum of 1 year of directly related experience.
  • Knowledge of molecular genetic principles.
  • Proficient in Python and R.
  • Strong consultation and communication skills.
  • Strong organizational and interpersonal skills for working in a multidiscipline and collaborative team.
  • Experience with next generation sequencing (NGS) methodologies and applications.
  • Experience in Linux/Unix systems

Preferred Qualifications

N/A

About UCSF

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.

Pride Values

UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.

In addition to our PRIDE values, UCSF is committed to equity - both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu

Join us to find a rewarding career contributing to improving healthcare worldwide.

Equal Employment Opportunity

The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.

Organization

Campus

Job Code and Payroll Title

009402 BIOINFORMATICS PROGR 2

Job Category

Clinical Systems / IT Professionals

Bargaining Unit

99 - Policy-Covered (No Bargaining Unit)

Employee Class

Career

Percentage

100%

Location

San Francisco, CA

Campus

Parnassus Heights (SF)

Work Style

Fully On-Site

Shift

Days

Shift Length

8 Hours

Additional Shift Details

Monday to Friday; 9am to 5:30pm

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